Interest in the human genome project reaches new heights

Hsp90 reaches new heights

Introduction Hsp90 (heat-shock protein 90) is an abundant molecular chaperone, but its function seems to be restricted to the folding of proteins involved in cell signalling, such as transcription factors and protein kinases. This restricted set of ‘clients’ (see Fig. 1) makes Hsp90 an attractive target for cancer therapeutics. As an anti-Hsp90 drug is now in clinical trials, the meeting was re...

Whole-brain imaging reaches new heights (and lengths)

Advances in microscopy and sample preparation have led to the first ever mapping of individual neurons in the whole mouse brain.

The Human Genome Project.

Dear readers, The last few decades have seen a number of exciting developments in genetics. First, Watson and Crick broke the genetic code; since then, tech-nologic and methodologic breakthroughs have permitted the study and direct manipulation of our DNA. Now there is an international ground swell to map and sequence the human genome. The Bush administration had originally requested $128 milli...

The Human Genome Project.

The Human Genome Project

genetic mapping; DNA; applied research; molecular genetics T Human Genome Project is an international research project whose primary mission is to decipher the chemical sequence of the complete human genetic material (i.e., the entire genome), identify all 50,000 to 100,000 genes contained within the genome, and provide research tools to analyze all this genetic information. This ambitious proj...